Detalhe da pesquisa
1.
Enzymatic Redox Properties and Cytotoxicity of Irreversible Nitroaromatic Thioredoxin Reductase Inhibitors in Mammalian Cells.
Int J Mol Sci
; 24(15)2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569833
2.
Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1).
Int J Mol Sci
; 21(22)2020 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228195
3.
Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity.
Int J Mol Sci
; 20(18)2019 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533349
4.
Mechanism of Two-/Four-Electron Reduction of Nitroaromatics by Oxygen-Insensitive Nitroreductases: The Role of a Non-Enzymatic Reduction Step.
Molecules
; 23(7)2018 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987261
5.
Naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity.
Bioorg Med Chem Lett
; 26(2): 512-517, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681508
6.
The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans).
Int J Mol Sci
; 15(12): 23307-31, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517035
7.
Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin-nitroreductase hybrid enzyme.
Arch Biochem Biophys
; 528(1): 50-6, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982531
8.
Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: a mechanistic study.
Arch Biochem Biophys
; 512(2): 183-9, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21664341
9.
5Flavoenzyme-catalyzed single-electron reduction of nitroaromatic antiandrogens: implications for their cytotoxicity.
Free Radic Res
; 55(3): 246-254, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34098820
10.
Quinones and nitroaromatic compounds as subversive substrates of Staphylococcus aureus flavohemoglobin.
Free Radic Biol Med
; 123: 107-115, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29793040
11.
Two-electron reduction of quinones by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.
Acta Biochim Pol
; 54(2): 379-85, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17546202
12.
Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives.
EXCLI J
; 16: 663-678, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28694766
13.
Reduction of nitroaromatic compounds by NAD(P)H:quinone oxidoreductase (NQO1): the role of electron-accepting potency and structural parameters in the substrate specificity.
Acta Biochim Pol
; 53(3): 569-76, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16929382
14.
Enzymatic redox reactions of the explosive 4,6-dinitrobenzofuroxan (DNBF): implications for its toxic action.
Acta Biochim Pol
; 51(4): 1081-6, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15625581
15.
Enzymatic redox properties of novel nitrotriazole explosives implications for their toxicity.
Z Naturforsch C J Biosci
; 59(5-6): 399-404, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-18998409
16.
Redox properties and prooxidant cytotoxicity of a neuroleptic agent 6,7-dinitrodihydroquinoxaline-2,3-dione (DNQX).
Acta Biochim Pol
; 60(2): 227-31, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23757451
17.
Structure-activity relationships in two-electron reduction of quinones.
Methods Enzymol
; 382: 258-77, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15047107
18.
FAD semiquinone stability regulates single- and two-electron reduction of quinones by Anabaena PCC7119 ferredoxin:NADP+ reductase and its Glu301Ala mutant.
Arch Biochem Biophys
; 437(2): 144-50, 2005 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15850554
19.
Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity.
Arch Biochem Biophys
; 425(2): 184-92, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15111126